There was a big debate about this film before, but I can't find the thread. I'll look around some more. Actually, it may have been deleted, it got a bit heated.
Personally, I thought it was dumb as dirt. Sure, it had a "horrific" concept, but that was it. The plot was contrived, the "science" was beyond stupid, and how it unfolded made no sense. It was Six's fetish film.
That is my opinion. If you disagree, I have no problems with that.